Predicting CAR-T cell Immunotherapy Success through ImmunoPET.

Authors :: Volpe A
Nagle VL
Lewis JS
Ponomarev V
Source :: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Feb 15; Vol. 27 (4), pp. 911-912. Date of Electronic Publication: 2020 Dec 16.
Publication Year :: 2021
Abstract: Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the in vivo dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells. See related article by Simonetta et al., p. 1058 .<br /> (©2020 American Association for Cancer Research.)

Subjects :: Humans
Immunotherapy
Immunotherapy, Adoptive
T-Lymphocytes
Hematologic Neoplasms
Receptors, Chimeric Antigen genetics

Language :: English
ISSN :: 1557-3265
Volume :: 27
Issue :: 4
Database :: MEDLINE
Journal :: Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Type :: Academic Journal
Accession number :: 33328345
Full Text :: https://doi.org/10.1158/1078-0432.CCR-20-4297