The Effect of Kidney Biopsy on Glomerular Filtration Rate: A Frequent Patient Concern.

Authors :: Dattani R
Corbett RW
Galliford J
Hill P
Cairns T
Cook HT
Roufosse C
Ashby DR
Source :: American journal of nephrology [Am J Nephrol] 2020 Dec 11, pp. 1-4. Date of Electronic Publication: 2020 Dec 11.
Publication Year :: 2020
Publisher :: Ahead of Print
Abstract: The effect of percutaneous kidney biopsy on glomerular filtration rate has never been identified, though it is frequently a concern raised by patients. Following a clinical interaction with an inquisitive patient undergoing her fifth biopsy, we attempted to estimate the effect using retrospective data. In a cohort of patients with stable kidney function undergoing transplant biopsy without clinical indication (as part of a surveillance programme) the effect of biopsy was observed as a step change in glomerular filtration rate. Reassuringly, the loss of glomerular filtration rate resulting from a biopsy, has a 1-sided 95% confidence interval of <1.4 mL/min.<br /> (© 2020 S. Karger AG, Basel.)

Full Text Access

Tools