Back to Search
Start Over
The gut-brain axis in irritable bowel syndrome and inflammatory bowel disease.
- Source :
-
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2021 Mar; Vol. 53 (3), pp. 298-305. Date of Electronic Publication: 2020 Dec 07. - Publication Year :
- 2021
-
Abstract
- Research increasingly demonstrates the bidirectional communication between gut microbiota and the brain, enhancing the role of gut microbiota modulation in the treatment of central nervous system (CNS) disorders. The first five years of life are extremely important as it affects the development of gut microbiota, immune system and, consequently, the onset of psychometric alterations, particularly in genetically predisposed individuals. In this review, we focus on the link between specific microbial genera, gastrointestinal (GI) disorders, anxiety and depression and on the effects of different therapeutic strategies for mood disorders on gut microbiota.<br />Competing Interests: Conflict of interest None declared.<br /> (Copyright © 2020 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Animals
Anxiety complications
Central Nervous System Agents therapeutic use
Depression complications
Gastrointestinal Microbiome drug effects
Humans
Inflammatory Bowel Diseases complications
Inflammatory Bowel Diseases physiopathology
Inflammatory Bowel Diseases psychology
Irritable Bowel Syndrome complications
Irritable Bowel Syndrome physiopathology
Mice
Psychiatric Status Rating Scales
Anxiety psychology
Brain-Gut Axis
Depression psychology
Irritable Bowel Syndrome psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3562
- Volume :
- 53
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
- Publication Type :
- Academic Journal
- Accession number :
- 33303315
- Full Text :
- https://doi.org/10.1016/j.dld.2020.11.026