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Two new phenolic glucosides from marine-derived fungus Aspergillus sp.

Authors :
Wen H
Zang Y
Zhu Q
Ouyang S
Luo J
Luo N
Zhu H
Zhang Y
Source :
Natural product research [Nat Prod Res] 2022 Jul; Vol. 36 (13), pp. 3255-3261. Date of Electronic Publication: 2020 Dec 08.
Publication Year :
2022

Abstract

Two new phenolic glucosides, including a new O -glycoside ( 1 ) and a new C -glycoside ( 2 ), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as β -D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization. All compounds were evaluated for their ability to inhibit LPS-induced NO production in RAW264.7 macrophages, but none of them displayed significant activity.

Details

Language :
English
ISSN :
1478-6427
Volume :
36
Issue :
13
Database :
MEDLINE
Journal :
Natural product research
Publication Type :
Academic Journal
Accession number :
33289426
Full Text :
https://doi.org/10.1080/14786419.2020.1851226