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End-point selection to determine the airway-systemic ratio of inhaled corticosteroids in asthma.
- Source :
-
British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 May; Vol. 87 (5), pp. 2401-2402. Date of Electronic Publication: 2020 Nov 23. - Publication Year :
- 2021
-
Abstract
- The use of adenosine monophosphate challenge and basal cortisol as short-term surrogate end points of airway-systemic effects of inhaled corticosteroids in asthma is not suitable to properly determine the clinically relevant long-term therapeutic index.<br /> (© 2020 British Pharmacological Society.)
Details
- Language :
- English
- ISSN :
- 1365-2125
- Volume :
- 87
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- British journal of clinical pharmacology
- Publication Type :
- Editorial & Opinion
- Accession number :
- 33230858
- Full Text :
- https://doi.org/10.1111/bcp.14633