Altered vitamin D metabolic system in follicular cysts of sows.

Authors :: Grzesiak M
Socha M
Hrabia A
Source :: Reproduction in domestic animals = Zuchthygiene [Reprod Domest Anim] 2021 Jan; Vol. 56 (1), pp. 193-196. Date of Electronic Publication: 2020 Dec 03.
Publication Year :: 2021
Abstract: This study aimed to examine 25OHD <subscript>3</subscript> concentration in the fluid of follicular and follicular lutein cysts of sows in comparison with preovulatory follicles as well as immunolocalize vitamin D metabolic enzymes (CYP27B1 and CYP24A1) and determine their protein abundances in the cyst wall. We have shown for the first time that 25OHD <subscript>3</subscript> level in the fluid of both cyst types was significantly lower than in preovulatory follicles. Furthermore, we have demonstrated CYP27B1 and CYP24A1 protein immunolocalization and abundance in follicular and follicular lutein cysts. The abundance of protein for both metabolic enzymes was decreased in ovarian cysts when compared to preovulatory follicles. We propose that altered VD metabolism in ovarian cyst might associate with their formation in sows.<br /> (© 2020 Wiley-VCH GmbH.)