Back to Search
Start Over
Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity.
- Source :
-
The Journal of cell biology [J Cell Biol] 2020 Dec 07; Vol. 219 (12). - Publication Year :
- 2020
-
Abstract
- The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.<br /> (© 2020 Zarnescu.)
- Subjects :
- Animals
Drosophila genetics
RNA, Messenger genetics
Centrosome
Mitosis
Subjects
Details
- Language :
- English
- ISSN :
- 1540-8140
- Volume :
- 219
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 33216116
- Full Text :
- https://doi.org/10.1083/jcb.202010172