Cost-Effectiveness of Screening, Surveillance, and Endoscopic Eradication Therapies for Managing the Burden of Esophageal Adenocarcinoma.

The authors conducted a review of the literature of cost-effectiveness analyses regarding management of Barrett's esophagus, including screening, surveillance, and treatment strategies. Because of the presence of multiple systematic reviews on this topic, they chose to focus on more recent economic analyses, with an emphasis on comparative modeling because these analyses have been demonstrated to achieve greater validity and impact when there are multiple competing strategies that are clinically reasonable to pursue. The authors identified areas of consensus across studies regarding management strategies and also areas that require additional empirical data.
Competing Interests: Disclosure Research effort provided for J.H. Rubenstein and J.M. Inadomi by the National Institutes for Health (U01CA152926, U01CA199336, U54CA163059). J.H. Rubenstein has served as a consultant to the American Gastroenterological Association Institute for work related to TissueCypher. J.M. Inadomi is on the scientific advisory board of Cernostics, which developed and produces TissueCypher.
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