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SAR Studies of the Leupyrrins: Design and Total Synthesis of Highly Potent Simplified Leupylogs.

Authors :
Wosniok PR
Knopf C
Dreisigacker S
Orozco-Rodriguez JM
Hinkelmann B
Mueller PP
Brönstrup M
Menche D
Source :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Nov 26; Vol. 26 (66), pp. 15051. Date of Electronic Publication: 2020 Nov 11.
Publication Year :
2020

Abstract

Invited for the cover of this issue is the group of Dirk Menche at the University of Bonn. The image depicts the natural product leupyrrin A <subscript>1</subscript> and a synthetic leupylog in balance on an IC50 weighing scale. Read the full text of the article at 10.1002/chem.202002622.<br /> (© 2020 Wiley-VCH GmbH.)

Details

Language :
English
ISSN :
1521-3765
Volume :
26
Issue :
66
Database :
MEDLINE
Journal :
Chemistry (Weinheim an der Bergstrasse, Germany)
Publication Type :
Academic Journal
Accession number :
33174290
Full Text :
https://doi.org/10.1002/chem.202003845