FGF23 and Cause-Specific Mortality in Community-Living Individuals-The Health, Aging, and Body Composition Study.

Authors :: Sharma S
Katz R
Dubin RF
Drew DA
Gutierrez OM
Shlipak MG
Sarnak MJ
Ix JH
Source :: Journal of the American Geriatrics Society [J Am Geriatr Soc] 2021 Mar; Vol. 69 (3), pp. 711-717. Date of Electronic Publication: 2020 Nov 10.
Publication Year :: 2021
Abstract: Objectives: Fibroblast growth factor (FGF)-23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C-terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause-specific mortality is unknown.<br />Design: Prospective analyses of data from Health, Aging, & Body Composition (HABC) study.<br />Setting: Community-living adults aged 70 to 79 years with longitudinal follow up.<br /> (© 2021 The American Geriatrics Society.)

Subjects :: Aged
Aging
Biomarkers blood
Cardiovascular Diseases mortality
Female
Fibroblast Growth Factor-23
Humans
Independent Living statistics & numerical data
Male
Prospective Studies
Cause of Death
Fibroblast Growth Factors blood

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