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Ensembl 2021.

Authors :
Howe KL
Achuthan P
Allen J
Allen J
Alvarez-Jarreta J
Amode MR
Armean IM
Azov AG
Bennett R
Bhai J
Billis K
Boddu S
Charkhchi M
Cummins C
Da Rin Fioretto L
Davidson C
Dodiya K
El Houdaigui B
Fatima R
Gall A
Garcia Giron C
Grego T
Guijarro-Clarke C
Haggerty L
Hemrom A
Hourlier T
Izuogu OG
Juettemann T
Kaikala V
Kay M
Lavidas I
Le T
Lemos D
Gonzalez Martinez J
Marugán JC
Maurel T
McMahon AC
Mohanan S
Moore B
Muffato M
Oheh DN
Paraschas D
Parker A
Parton A
Prosovetskaia I
Sakthivel MP
Salam AIA
Schmitt BM
Schuilenburg H
Sheppard D
Steed E
Szpak M
Szuba M
Taylor K
Thormann A
Threadgold G
Walts B
Winterbottom A
Chakiachvili M
Chaubal A
De Silva N
Flint B
Frankish A
Hunt SE
IIsley GR
Langridge N
Loveland JE
Martin FJ
Mudge JM
Morales J
Perry E
Ruffier M
Tate J
Thybert D
Trevanion SJ
Cunningham F
Yates AD
Zerbino DR
Flicek P
Source :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 08; Vol. 49 (D1), pp. D884-D891.
Publication Year :
2021

Abstract

The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed and comprehensive annotation of gene structures, regulatory elements and variants, and enable comparative genomics by inferring the evolutionary history of genes and genomes. Our integrated genomic data are made available in a variety of ways, including genome browsers, search interfaces, specialist tools such as the Ensembl Variant Effect Predictor, download files and programmatic interfaces. Here, we present recent Ensembl developments including two new website portals. Ensembl Rapid Release (http://rapid.ensembl.org) is designed to provide core tools and services for genomes as soon as possible and has been deployed to support large biodiversity sequencing projects. Our SARS-CoV-2 genome browser (https://covid-19.ensembl.org) integrates our own annotation with publicly available genomic data from numerous sources to facilitate the use of genomics in the international scientific response to the COVID-19 pandemic. We also report on other updates to our annotation resources, tools and services. All Ensembl data and software are freely available without restriction.<br /> (© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.)

Details

Language :
English
ISSN :
1362-4962
Volume :
49
Issue :
D1
Database :
MEDLINE
Journal :
Nucleic acids research
Publication Type :
Academic Journal
Accession number :
33137190
Full Text :
https://doi.org/10.1093/nar/gkaa942