AlignmentViewer: Sequence Analysis of Large Protein Families.

Authors :: Reguant R
Antipin Y
Sheridan R
Dallago C
Diamantoukos D
Luna A
Sander C
Gauthier NP
Source :: F1000Research [F1000Res] 2020 Mar 27; Vol. 9. Date of Electronic Publication: 2020 Mar 27 (Print Publication: 2020).
Publication Year :: 2020
Abstract: AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org.<br />Competing Interests: No competing interests were disclosed.<br /> (Copyright: © 2020 Reguant R et al.)