Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis.

Authors :: Sasikumar PK
Varghese SS
Kumaran T
Devi SS
Source :: Contemporary clinical dentistry [Contemp Clin Dent] 2020 Jan-Mar; Vol. 11 (1), pp. 3-9. Date of Electronic Publication: 2020 Jul 13.
Publication Year :: 2020
Abstract: The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.<br />Competing Interests: There are no conflicts of interest.<br /> (Copyright: © 2020 Contemporary Clinical Dentistry.)

Full Text Access

Tools