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[Polycystic ovary syndrome in obese or type 1 diabetic (T1D) adolescent girls].

Authors :
Bouthors T
Elowe-Gruau É
Antoniou MC
Hryciuk J
Stoppa-Vaucher S
Ruiz Arana IL
Diserens C
Busiah K
Hauschild M
Source :
Revue medicale suisse [Rev Med Suisse] 2020 Oct 14; Vol. 16 (710), pp. 1941-1944.
Publication Year :
2020

Abstract

Polycystic ovary syndrome (PCOS) is frequent during adolescence (prevalence ≈ 6 %), and the prevalence increases in obese or type 1 diabetic (T1D) adolescent girls. During puberty, PCOS diagnosis is difficult because of the overlap with some pubertal physiologic signs. The 2017 international consortium suggests two required diagnostic criteria: persistent menstrual disturbances and hyperandrogenism. PCOS physiopathology is complex, including interactions between genetic, epigenetic factors, primary ovarian abnormalities, neuroendocrine alterations, hormonal and metabolic factors. Insulin seems to have a central place in obese or T1D adolescent girls. The treatment is still debated and should be monitored according to the main symptoms.<br />Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

Details

Language :
French
ISSN :
1660-9379
Volume :
16
Issue :
710
Database :
MEDLINE
Journal :
Revue medicale suisse
Publication Type :
Academic Journal
Accession number :
33058582