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Systemic Listeria monocytogenes infection and concurrent pleural mesothelioma in a cat.
- Source :
-
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2021 Jan; Vol. 33 (1), pp. 120-123. Date of Electronic Publication: 2020 Oct 15. - Publication Year :
- 2021
-
Abstract
- Herein we describe a rare case of systemic Listeria monocytogenes infection with concurrent pleural mesothelioma in a stray cat that was found dead and submitted for autopsy. Gross pathology changes consisted of thoracic clear yellow fluid admixed with suspended fibrin strands; clear-to-tan, variably sized, <3 mm diameter pulmonary nodules; and enlargement of the submandibular, retropharyngeal, and prescapular lymph nodes. Histologic changes consisted of extensive areas of suppurative inflammation and necrosis with mineralization that partially effaced the pulmonary parenchyma and lymph nodes. Random, distinct necrotic foci were present throughout the hepatic parenchyma. Extending from the pleura, within perinecrotic alveolar spaces, and infiltrating the submandibular, retropharyngeal, and prescapular lymph nodes were dense sheets of neoplastic epithelioid cells with moderate pleomorphism and occasional karyomegaly and multinucleation. Neoplastic cells exhibited immunolabeling for pancytokeratin AE1/AE3 and vimentin, consistent with pleural mesothelioma. Aerobic bacterial culture of lung yielded heavy growth of L. monocytogenes . Immunohistochemistry (IHC) for L. monocytogenes revealed clusters of bacteria in the lung, lymph node, and liver. Pathologic changes were consistent with systemic listeriosis, confirmed by bacterial culture and IHC, and concurrent pleural mesothelioma.
- Subjects :
- Animals
Cat Diseases microbiology
Cats
Diagnosis, Differential
Female
Listeriosis complications
Listeriosis diagnosis
Listeriosis microbiology
Mesothelioma complications
Mesothelioma pathology
Pleural Neoplasms complications
Pleural Neoplasms pathology
Cat Diseases diagnosis
Listeria monocytogenes isolation & purification
Listeriosis veterinary
Mesothelioma veterinary
Pleural Neoplasms veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1943-4936
- Volume :
- 33
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Publication Type :
- Academic Journal
- Accession number :
- 33054600
- Full Text :
- https://doi.org/10.1177/1040638720966321