Back to Search
Start Over
Clinical Relevance of Skin Pain in Atopic Dermatitis.
- Source :
-
Journal of drugs in dermatology : JDD [J Drugs Dermatol] 2020 Oct 01; Vol. 19 (10), pp. 921-926. - Publication Year :
- 2020
-
Abstract
- Skin pain is increasingly recognized as an impactful symptom in atopic dermatitis (AD) because of its association with patient discomfort, disease burden, and reduced quality of life. Although the nature of skin pain in AD has not been systematically studied and is therefore not well understood, patients report soreness, discomfort, and tenderness that may reflect peripheral and central pain sensitization. The high prevalence of skin pain suggests that it is not adequately addressed by current therapies for AD and may be undertreated compared with other symptoms. This review discusses the clinical relevance of skin pain with respect to its experience, pathophysiology, relationship with itch, and treatment implications. Recent studies suggest that skin pain presents as a neuropathic symptom independent from itch and the “itch-scratch cycle”, and poses a unique burden to patients. Recognition of the significant consequences of skin pain and discomfort should reinforce the need to assess and treat this symptom in patients with moderate-to-severe AD. J Drugs Dermatol. 2020;19(10)921-926. doi:10.36849/JDD.2020.5498.
- Subjects :
- Cost of Illness
Dermatitis, Atopic complications
Dermatitis, Atopic immunology
Dermatitis, Atopic psychology
Humans
Pain diagnosis
Pain epidemiology
Pain Measurement
Prevalence
Pruritus immunology
Pruritus psychology
Severity of Illness Index
Skin immunology
Skin innervation
Skin pathology
Surveys and Questionnaires
Dermatitis, Atopic diagnosis
Pain immunology
Pruritus diagnosis
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1545-9616
- Volume :
- 19
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of drugs in dermatology : JDD
- Publication Type :
- Academic Journal
- Accession number :
- 33026764
- Full Text :
- https://doi.org/10.36849/JDD.2020.5498