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[Oncogene products as tumor markers].

Authors :
Shiku H
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 1987 Jun; Vol. 14 (6 Pt 2), pp. 2212-7.
Publication Year :
1987

Abstract

Monoclonal antibodies reactive with ras gene products were produced. Specificity of the antibodies obtained was determined by ELISA and immunoblotting assays. Using one of those anti-ras p21 monoclonal antibodies, RASK-3 the expression of p21 in human stomach cancer and thyroid cancer was studied by means of immuno-histochemistry. ras p21 was more dominantly expressed in cancer cells than in normal epithelial cells.

Subjects

Subjects :
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Humans
Proto-Oncogene Proteins p21(ras)
Stomach Neoplasms diagnosis
Thyroid Neoplasms diagnosis
Antibodies, Monoclonal
Neoplasms diagnosis
Oncogenes
Proto-Oncogene Proteins immunology

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
14
Issue :
6 Pt 2
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
3300559

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