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Intracranial Arterial Calcification: Prevalence, Risk Factors, and Consequences: JACC Review Topic of the Week.
- Source :
-
Journal of the American College of Cardiology [J Am Coll Cardiol] 2020 Sep 29; Vol. 76 (13), pp. 1595-1604. - Publication Year :
- 2020
-
Abstract
- Intracranial large and small arterial calcifications are a common incidental finding on computed tomography imaging in the general population. Here we provide an overview of the published reports on prevalence of intracranial arterial calcifications on computed tomography imaging and histopathology in relation to risk factors and clinical outcomes. We performed a systematic search in Medline, with a search filter using synonyms for computed tomography scanning, (histo)pathology, different intracranial arterial beds, and calcification. We found that intracranial calcifications are a frequent finding in all arterial beds with the highest prevalence in the intracranial internal carotid artery. In general, prevalence increases with age. Longitudinal studies on calcification progression and intervention studies are warranted to investigate the possible causal role of calcification on clinical outcomes. This might open up new therapeutic directions in stroke and dementia prevention and the maintenance of the healthy brain.<br /> (Copyright © 2020 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Arteries diagnostic imaging
Humans
Intracranial Arterial Diseases diagnostic imaging
Intracranial Arterial Diseases pathology
Neuroimaging
Prevalence
Risk Factors
Tomography, X-Ray Computed
Vascular Calcification diagnostic imaging
Vascular Calcification pathology
Arteries pathology
Intracranial Arterial Diseases epidemiology
Vascular Calcification epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1558-3597
- Volume :
- 76
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Journal of the American College of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 32972537
- Full Text :
- https://doi.org/10.1016/j.jacc.2020.07.056