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Analysis of PEG 400 in perfusate samples by aqueous normal phase (ANP) chromatography with evaporative light scattering detection.
- Source :
-
Analytical methods : advancing methods and applications [Anal Methods] 2011 Mar 01; Vol. 3 (3), pp. 742-744. - Publication Year :
- 2011
-
Abstract
- A rapid method for the analysis of polyethylene glycol (PEG 400) in perfusate samples is presented. Because PEG 400 lacks a strong chromophore in the UV range, detection was accomplished using evaporative light scattering detection (ELSD). In order to optimize the ELSD signal performance for a volatile mobile phase, the chromatographic separation was optimized using aqueous normal phase conditions on a Cogent® Diamond Hydride column.
Details
- Language :
- English
- ISSN :
- 1759-9679
- Volume :
- 3
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Analytical methods : advancing methods and applications
- Publication Type :
- Academic Journal
- Accession number :
- 32938100
- Full Text :
- https://doi.org/10.1039/c0ay00698j