The acceleration of ageing in older patients with cancer.

Authors :: Muhandiramge J
Orchard S
Haydon A
Zalcberg J
Source :: Journal of geriatric oncology [J Geriatr Oncol] 2021 Apr; Vol. 12 (3), pp. 343-351. Date of Electronic Publication: 2020 Sep 12.
Publication Year :: 2021
Abstract: Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.<br />Competing Interests: Declaration of Competing Interest The authors have no conflicts of interest to report.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)