Coagulation factors induce human skin mast cell and basophil degranulation via activation of complement 5 and the C5a receptor.

Authors :: Yanase Y
Matsuo Y
Takahagi S
Kawaguchi T
Uchida K
Ishii K
Tanaka A
Matsubara D
Ozawa K
Hide M
Source :: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Mar; Vol. 147 (3), pp. 1101-1104.e7. Date of Electronic Publication: 2020 Sep 02.
Publication Year :: 2021

Subjects :: Cell Degranulation
Cells, Cultured
Histamine Release
Humans
Basophils immunology
Blood Coagulation Factors metabolism
Chronic Urticaria immunology
Complement C5 metabolism
Mast Cells immunology
Receptor, Anaphylatoxin C5a metabolism
Skin immunology

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