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Ocular hypertension following 40 mg sub-Tenon triamcinolone versus 0.7 mg dexamethasone implant versus 2 mg intravitreal triamcinolone.
- Source :
-
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie [Can J Ophthalmol] 2020 Dec; Vol. 55 (6), pp. 480-485. Date of Electronic Publication: 2020 Aug 24. - Publication Year :
- 2020
-
Abstract
- Objective: To compare rates of ocular hypertension (OHT) in eyes receiving 40 mg sub-Tenon triamcinolone (STT), 0.7 mg dexamethasone implant (DEX), and 2 mg intravitreal triamcinolone (IVT).<br />Methods: This study is a single-centre, retrospective case series. All patients receiving STT and DEX between 4/1/2014 and 3/1/2017 and IVT between 3/1/2012 and 3/1/2017 with a minimum of 3 months' follow-up were included. OHT was defined as an intraocular pressure (IOP) >24 mm Hg. Patients receiving any other form of topical, oral, or intravitreal steroid were excluded.<br />Results: 113 eyes from 104 patients in the STT group, 122 eyes from 109 patients in the DEX group, and 109 eyes from 103 patients in the IVT group were included. The mean number of injections for each eye was 1.7 in the STT group, 2.6 for the DEX group, and 2.8 for the IVT group (p < 0.001). Twenty eyes (17.7%) developed OHT in the STT group, 19 eyes (15.6%) developed OHT in the DEX group, and 14 eyes (12.8%) developed OHT in the IVT group (p = 0.60). IOP was controlled in all eyes with observation, topical IOP-lowering medication, or surgical intervention. The rate of incisional glaucoma surgery was 1.7% in the STT group, 1.6% in the DEX group, and 0% in the IVT group (p = 0.55).<br />Conclusions: The rate of OHT was similar across treatment groups. The proportion of OHT in patients with a history of glaucoma was no different from that in patients without a history of glaucoma. All cases were successfully managed with observation, medical treatment, or incisional surgery.<br /> (Copyright © 2020 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Dexamethasone adverse effects
Follow-Up Studies
Glucocorticoids adverse effects
Humans
Intraocular Pressure
Intravitreal Injections
Retrospective Studies
Triamcinolone Acetonide adverse effects
Glaucoma chemically induced
Glaucoma drug therapy
Ocular Hypertension chemically induced
Ocular Hypertension diagnosis
Ocular Hypertension drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1715-3360
- Volume :
- 55
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
- Publication Type :
- Academic Journal
- Accession number :
- 32853591
- Full Text :
- https://doi.org/10.1016/j.jcjo.2020.06.021