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The C3-H Bond Functionalization of Quinoxalin-2(1 H )-Ones With Hypervalent Iodine(III) Reagents.
- Source :
-
Frontiers in chemistry [Front Chem] 2020 Aug 03; Vol. 8, pp. 582. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- The modification of quinoxalin-2(1 H )-ones via direct C-H bond functionalization has begun to receive widespread attention, due to quinoxalin-2(1 H )-one derivatives' various biological activities and pharmaceutical properties. This mini review concentrates on the accomplishments of arylation, trifluoromethylation, alkylation, and alkoxylation of quinoxalin-2(1 H )-ones with hypervalent iodine(III) reagents as reaction partners or oxidants. The reaction conditions and mechanisms are compared and discussed in detail.<br /> (Copyright © 2020 Tan, Wang, Zhang, Zhang and Zhao.)
Details
- Language :
- English
- ISSN :
- 2296-2646
- Volume :
- 8
- Database :
- MEDLINE
- Journal :
- Frontiers in chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 32850624
- Full Text :
- https://doi.org/10.3389/fchem.2020.00582