Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic.

Authors :: El-Khatib L
Alrayes H
Sallam O
Elbanna A
Source :: BMJ case reports [BMJ Case Rep] 2020 Aug 24; Vol. 13 (8). Date of Electronic Publication: 2020 Aug 24.
Publication Year :: 2020
Abstract: Quinidine is one of the oldest antiarrhythmics known. Over the years, its use has decreased along with its side effects. Our case describes a 69-year-old woman with recurrent resistant ventricular tachycardia on Quinidine and Amiodarone who presented with acute liver toxicity. Drug-induced liver toxicity was at the top of our differential diagnosis list. Taking multiple factors into consideration, a decision was made to discontinue Quinidine, the patient's symptoms and lab abnormalities resolved within 1 week, yielding the diagnosis of Quinidine hypersensitivity.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.)