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SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19.

Authors :
Anderson EM
Diorio C
Goodwin EC
McNerney KO
Weirick ME
Gouma S
Bolton MJ
Arevalo CP
Chase J
Hicks P
Manzoni TB
Baxter AE
Andrea KP
Burudpakdee C
Lee JH
Vella LA
Henrickson SE
Harris RM
Wherry EJ
Bates P
Bassiri H
Behrens EM
Teachey DT
Hensley SE
Source :
MedRxiv : the preprint server for health sciences [medRxiv] 2020 Aug 18. Date of Electronic Publication: 2020 Aug 18.
Publication Year :
2020

Abstract

SARS-CoV-2 antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike IgG titers compared to those with severe coronavirus disease 2019 (COVID-19), likely reflecting a longer time since onset of infection in MIS-C patients.

Details

Language :
English
Database :
MEDLINE
Journal :
MedRxiv : the preprint server for health sciences
Publication Type :
Academic Journal
Accession number :
32839782
Full Text :
https://doi.org/10.1101/2020.08.17.20176552