Update on Albumin Therapy in Critical Illness.

Authors :: Mazzaferro EM
Edwards T
Source :: The Veterinary clinics of North America. Small animal practice [Vet Clin North Am Small Anim Pract] 2020 Nov; Vol. 50 (6), pp. 1289-1305. Date of Electronic Publication: 2020 Aug 21.
Publication Year :: 2020
Abstract: Albumin is among the most important proteins and plays a significant role in maintenance of colloid osmotic pressure, wound healing, decreasing oxidative damage, carrying drugs and endogenous substances, and coagulation. Hypoalbuminemia is common in acute and chronic illnesses. Replenishment of albumin can be in the form of fresh frozen, frozen or cryopoor plasma, or in the form of human or canine albumin concentrates. Infusion of human albumin concentrate to healthy and critically ill dogs can induce acute and delayed hypersensitivity reactions. Death has been reported. Therefore, allogenic transfusion in the form of plasma products or canine albumin concentrate is recommended.<br />Competing Interests: Disclosure The views expressed in this article are those of the authors and do not reflect the official policy or position of the US Army Medical Department, Departments of the Army, the Department of Defense, or the US Government.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)