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Review of dysthymia and persistent depressive disorder: history, correlates, and clinical implications.
- Source :
-
The lancet. Psychiatry [Lancet Psychiatry] 2020 Sep; Vol. 7 (9), pp. 801-812. - Publication Year :
- 2020
-
Abstract
- Persistent depressive disorder is a chronic mood disorder that is common and often more disabling than episodic major depression. In DSM-5, the term subsumes several chronic depressive presentations, including dysthymia with or without superimposed major depressive episodes, chronic major depression, and recurrent major depression without recovery between episodes. Dysthymia can be difficult to detect in psychiatric and primary care settings until it intensifies in the form of a superimposed major depressive episode. Although information is scarce concerning the cause of persistent depressive disorder including dysthymia, the causation is likely to be multifactorial. In this narrative Review, we discuss current knowledge about the nosology and neurobiological basis of dysthymia and persistent depressive disorder, emphasising a dimensional perspective based on course for further research. We also review new developments in psychotherapy and pharmacotherapy for persistent depressive disorder, and propose a tailored, modular approach to accommodate its multifaceted nature.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)
- Subjects :
- Antidepressive Agents therapeutic use
Chronic Disease
Combined Modality Therapy
Comorbidity
Depressive Disorder, Major epidemiology
Diagnostic and Statistical Manual of Mental Disorders
Dysthymic Disorder epidemiology
Humans
Psychotherapy methods
Recurrence
Depressive Disorder, Major diagnosis
Depressive Disorder, Major therapy
Dysthymic Disorder diagnosis
Dysthymic Disorder therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2215-0374
- Volume :
- 7
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The lancet. Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 32828168
- Full Text :
- https://doi.org/10.1016/S2215-0366(20)30099-7