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68Ga-FAPI PET/CT in Assessment of Leptomeningeal Metastases in a Patient With Lung Adenocarcinoma.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2020 Oct; Vol. 45 (10), pp. 784-786. - Publication Year :
- 2020
-
Abstract
- We presented a case of 64-year-old woman with pathologically diagnosed lung adenocarcinoma. Brain metastases were highly suspected due to the appearance of neurological symptoms. However, no abnormal finding in the brain was observed on F-FDG PET/CT. Contrast-enhanced MRI showed the presence of leptomeningeal metastases but with a negative cerebrospinal fluid analysis. For this reason, the patient underwent Ga-FAPI PET/CT, later fused with MRI scans that showed intense uptake of Ga-FAPI in leptomeningeal regions correspondent to the sites of gadolinium enhancement. This case highlights that Ga-FAPI would be promising for the identification of leptomeningeal involvement in patients with malignant disease.
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 45
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 32796242
- Full Text :
- https://doi.org/10.1097/RLU.0000000000003231