Complete surgical removal of multiple tumor lesions in malignant pheochromocytomas produces a good prognosis.

Introduction: Malignant pheochromocytomas are rare catecholamine secreting tumors; there is no definitive strategy for the treatment of malignant pheochromocytomas, especially in cases with multiple tumors.
Case Presentation: A 72-year-old woman with diabetic ketoacidosis presented with multiple malignant pheochromocytomas 16 years after undergoing adrenalectomy. After three courses of systemic chemotherapy, there was no change in the size of tumor lesions or serum catecholamine levels; surgical removal of all lesions was carried out. Eighteen months after the operation, the patient has had no recurrences and her diabetes is controlled well by oral medication.
Conclusion: Our findings indicate that complete surgical resection should be considered, even in patients with multiple malignant pheochromocytomas.
Competing Interests: The authors declare no conflict of interest.
(© 2019 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association.)