[Raynaud phenomenon with arterial thromboses and IgG4-related disease].

Authors :: Lenfant T
Moroch J
de Risi-Pugliese T
Monfort JB
Benjoar M
Barbaud A
Senet P
Source :: La Revue de medecine interne [Rev Med Interne] 2020 Oct; Vol. 41 (10), pp. 708-713. Date of Electronic Publication: 2020 Jul 27.
Publication Year :: 2020
Abstract: Introduction: This is a clinical case illustrating a diagnosis of an IgG4 related-disease (IgG4-RD) diagnosed in a vascular context.<br />Case Report: A 47-year-old man with no past medical history consulted for a recent and disabling Raynaud phenomenon without trophic disorder. Vascular examinations revealed multiple arterial thromboses with no abnormal finger and toe pressures. Secondly, weight loss and submandibular glands enlargement appeared, leading to the diagnosis of IgG4-RD without a link being able to be established with vascular involvement. This is the second observation of this association. A French translation of the new classification criteria for IgG4-RD published in 2019 by the American College of Rheumatology and European Ligue Against Rhumatism (ACR/EULAR) is offered with direct application to the clinical case.<br />Conclusion: A Raynaud phenomenon with distal arterial thrombosis is rarely observed in the IgG4-RD.<br /> (Copyright © 2020. Published by Elsevier Masson SAS.)