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Immune-Mediated Neuropathies.
- Source :
-
Neurologic clinics [Neurol Clin] 2020 Aug; Vol. 38 (3), pp. 711-735. Date of Electronic Publication: 2020 Jun 11. - Publication Year :
- 2020
-
Abstract
- The immune-mediated neuropathies are a broad category of diseases differentiated by time course, affected nerve fibers, and disease associations. This article spans the common, well-defined inflammatory demyelinating polyradiculoneuropathies (Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy) to the rarer, acquired demyelinating neuropathy variants (Miller-Fisher syndrome and multifocal motor neuropathy), vasculitic neuropathies, and sensory neuronopathies (dorsal root ganglionopathies). These case studies illustrate the characteristic clinical patterns of the immune-mediated neuropathies encountered in neurologic practice. Recommendations for diagnostic evaluation and treatment approach accompany each case. Prompt recognition of these disorders is imperative; delays in treatment may result in prolonged morbidity and permanent disability.<br />Competing Interests: Disclosure Dr K.G. Gwathmey serves as a consultant to Alexion pharmaceuticals. Dr A.G. Smith serves as a consultant to Alexion, Argenx, Disarm, and Regenesis, and receives research funding from NINDS and NIDDK.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Guillain-Barre Syndrome therapy
Humans
Male
Middle Aged
Miller Fisher Syndrome therapy
Polyneuropathies therapy
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating therapy
Guillain-Barre Syndrome diagnostic imaging
Guillain-Barre Syndrome immunology
Miller Fisher Syndrome diagnostic imaging
Miller Fisher Syndrome immunology
Polyneuropathies diagnostic imaging
Polyneuropathies immunology
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating diagnostic imaging
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1557-9875
- Volume :
- 38
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Neurologic clinics
- Publication Type :
- Academic Journal
- Accession number :
- 32703478
- Full Text :
- https://doi.org/10.1016/j.ncl.2020.03.008