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Treating COVID-19: Review of Drug Hypersensitivity Reactions.
- Source :
-
Journal of investigational allergology & clinical immunology [J Investig Allergol Clin Immunol] 2020; Vol. 30 (6), pp. 385-399. Date of Electronic Publication: 2020 Jul 23. - Publication Year :
- 2020
-
Abstract
- The disease caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ie, coronavirus disease 2019 (COVID-19), has become a global pandemic since it was first reported in Wuhan, China in December 2019. Its severe clinical manifestations, which often necessitate admission to intensive care units, and high mortality rate represent a therapeutic challenge for the medical community. To date, no drugs have been approved for its treatment, and various therapeutic options are being assayed to address the pathophysiological processes underlying the clinical manifestations experienced by patients. New and old drugs administered as monotherapy or in combination to immunologically compromised patients may favor the development of adverse drug reactions, including drug hypersensitivity reactions, which must be identified and managed accordingly. Given the lack of herd immunity and the high rate of viral contagion, new cases are expected to emerge in the coming months. Thus, the probability of more adverse reactions or even new clinical manifestations may increase in parallel. Allergists must receive updated information on these treatments, as well as on the management of possible drug hypersensitivity reactions.
- Subjects :
- Antiviral Agents adverse effects
Antiviral Agents therapeutic use
COVID-19 complications
COVID-19 immunology
COVID-19 pathology
Cytokines antagonists & inhibitors
Diagnosis, Differential
Humans
Hypersensitivity, Delayed diagnosis
Hypersensitivity, Delayed etiology
Hypersensitivity, Immediate diagnosis
Hypersensitivity, Immediate etiology
Immunologic Factors adverse effects
Immunologic Factors therapeutic use
SARS-CoV-2
Drug Hypersensitivity diagnosis
Drug Hypersensitivity etiology
COVID-19 Drug Treatment
Subjects
Details
- Language :
- English
- ISSN :
- 1018-9068
- Volume :
- 30
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of investigational allergology & clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 32700681
- Full Text :
- https://doi.org/10.18176/jiaci.0588