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Genetic diversity and evolutionary history of Korean isolates of severe fever with thrombocytopenia syndrome virus from 2013-2016.
- Source :
-
Archives of virology [Arch Virol] 2020 Nov; Vol. 165 (11), pp. 2599-2603. Date of Electronic Publication: 2020 Jul 22. - Publication Year :
- 2020
-
Abstract
- Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV). Although SFTS originated in China, it is an emerging infectious disease with prevalence confirmed in Japan, Korea, and Vietnam. The full-length genomes of 51 Korean SFTSV isolates from 2013 to 2016 were sequenced, and the sequences were deposited into a public database (GenBank) and analyzed to elucidate the phylogeny and evolution of the virus. Although most of the Korean SFTSV isolates were closely related to previously reported Japanese isolates, some were closely related to previously reported Chinese isolates. We identified one Korean strain that appears to have resulted from multiple inter-lineage reassortments. Several nucleotide and amino acid variations specific to the Korean isolates were identified. Future studies should focus on how these variations affect virus pathogenicity and evolution.
- Subjects :
- Base Sequence
China
Evolution, Molecular
Genetic Variation
Genotype
Humans
Japan
Phlebovirus classification
Phlebovirus isolation & purification
Phylogeny
Republic of Korea
Sequence Analysis, DNA
Thrombocytopenia virology
Bunyaviridae Infections virology
Phlebotomus Fever virology
Phlebovirus genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1432-8798
- Volume :
- 165
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Archives of virology
- Publication Type :
- Academic Journal
- Accession number :
- 32699980
- Full Text :
- https://doi.org/10.1007/s00705-020-04733-0