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Pneumonitis from immune checkpoint inhibitors and COVID-19: current concern in cancer treatment.

Authors :
Rossi E
Schinzari G
Tortora G
Source :
Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Jul; Vol. 8 (2).
Publication Year :
2020

Abstract

Pneumonitis is a rare but serious adverse event caused by cancer immunotherapy. The diagnosis between COVID-19-induced pneumonia and immunotherapy-induced pneumonitis may be challenging in the era of COVID-19 outbreak. Some clinical symptoms and radiological findings of pneumonitis can be attributed to the coronavirus infection as well as to an immune-related adverse event. Identifying the exact cause of a pneumonitis in patients on treatment with immunotherapy is crucial to promptly start the most appropriate treatment. The proper management of immune checkpoint inhibitors for the risk of pneumonia must take into account a series of parameters. Accurate attention should be payed to symptoms like cough, fever and dyspnea during immunotherapy.<br />Competing Interests: Competing interests: None declared.<br /> (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Details

Language :
English
ISSN :
2051-1426
Volume :
8
Issue :
2
Database :
MEDLINE
Journal :
Journal for immunotherapy of cancer
Publication Type :
Academic Journal
Accession number :
32699182
Full Text :
https://doi.org/10.1136/jitc-2020-000952