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Detection of Mycobacterium Tuberculosis DNA in Buccal Swab Samples from Children in Lima, Peru.
- Source :
-
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2020 Nov; Vol. 39 (11), pp. e376-e380. - Publication Year :
- 2020
-
Abstract
- We examined Mycobacterium tuberculosis DNA detection from buccal swab samples collected from children in Lima, Peru. DNA was extracted and amplified via real-time polymerase chain reaction. Sensitivity was 21% (95% confidence interval [CI]: 7%-42%) in 24 culture-confirmed tuberculosis cases and 4.6% (95% CI: 1%-13%) in 65 clinically diagnosed unconfirmed cases. Sensitivity was highest for smear-positive tuberculosis. Specificity was 99% in the 199 controls (95% CI: 96%-100%).
Details
- Language :
- English
- ISSN :
- 1532-0987
- Volume :
- 39
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- The Pediatric infectious disease journal
- Publication Type :
- Academic Journal
- Accession number :
- 32675773
- Full Text :
- https://doi.org/10.1097/INF.0000000000002828