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Perinatal outcome in case of maternal death for cerebrovascular acute disorders: a nationwide study in Japan.
- Source :
-
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2022 Jul; Vol. 35 (13), pp. 2429-2434. Date of Electronic Publication: 2020 Jul 16. - Publication Year :
- 2022
-
Abstract
- Objective: The goal of this study is to find clues to improve perinatal outcomes in the case of cerebrovascular acute disorders during pregnancy.<br />Study Design: We analyzed 35 cases of cerebrovascular diseases related to maternal deaths in Japan those that occurred during pregnancy and reported to the Committee of the Ministry of Health, Labor, and Welfare from 2010 to 2018.<br />Results: Cerebrovascular acute disorders occurred at 34.6 ± 6.6 gestational weeks. There were seven intrauterine fetal deaths (IUFD), and eight cases showed neonatal asphyxia with umbilical arterial pH between 6.7 and 7.0 (asphyxia cases, n = 15). In two of eight newborns, brain hypothermia therapy was given, and all survived without neurological sequelae. Maternal dyspnea was significantly related to severe prolonged decelerations of the fetus ( p < .05), and asphyxia cases ( p < .005). Median time from maternal onset to delivery (OD time) was significantly longer in asphyxia cases than in the non-asphyxia cases (84 vs 29 min, p < .05). OD time over 30 min was significantly related to the antepartum occurrence, cervical dilatation <5 cm ( p < .05), onset outside of the hospital ( p < .001), and maternal transfer before delivery ( p < .001).<br />Conclusion: More than 40% of cases experienced fetal asphyxia, and 20% ended in IUFD in maternal deaths related to cerebrovascular acute disorders. Maternal respiratory support and rapid delivery would be the keys to improve perinatal outcomes in case of cerebrovascular acute disorders during pregnancy.
- Subjects :
- Asphyxia complications
Female
Humans
Infant, Newborn
Japan epidemiology
Maternal Mortality
Pregnancy
Asphyxia Neonatorum complications
Asphyxia Neonatorum epidemiology
Asphyxia Neonatorum therapy
Cerebrovascular Disorders complications
Cerebrovascular Disorders therapy
Maternal Death
Perinatal Death etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1476-4954
- Volume :
- 35
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Publication Type :
- Academic Journal
- Accession number :
- 32674694
- Full Text :
- https://doi.org/10.1080/14767058.2020.1786511