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New heterocyclic ring systems--V synthesis and pharmacological activity of 6H-1,3,4-thiadiazolo [3',2':1,2]-5-oxopyrimido [5,4-b] indole derivatives and of 1-phenyl-6H-1,2,4-triazolo [1',5':1,2]-5-oxopyrimido[5,4-b] indole.

Authors :
Russo F
Guccione S
Santagati NA
Santagati A
Caruso A
Leone MG
Felice A
Attaguile G
Amico Roxas M
Source :
Il Farmaco; edizione scientifica [Farmaco Sci] 1988 May; Vol. 43 (5), pp. 409-20.
Publication Year :
1988

Abstract

As a part of a study on analgesic and antiinflammatory active condensed heterocyclic compounds containing the pyrimidinic ring, a number of 6H-1,3,4-thiadiazolo [3',2':1,2]-5-oxopyrimido [5,4-b]indole and 1-phenyl-6H-1,2,4-triazolo [1',5':1,2]-5-oxopyrimido [5,4-b] indole were synthesized and tested. The results of pharmacological assays are reported and discussed.

Details

Language :
English
ISSN :
0430-0920
Volume :
43
Issue :
5
Database :
MEDLINE
Journal :
Il Farmaco; edizione scientifica
Publication Type :
Academic Journal
Accession number :
3265391