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Surgical management of submacular hemorrhage due to n-AMD: a comparison of three surgical methods.
- Source :
-
International journal of retina and vitreous [Int J Retina Vitreous] 2020 Jul 02; Vol. 6, pp. 27. Date of Electronic Publication: 2020 Jul 02 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Background: To compare and assess the efficacy of three surgical methods for the treatment of acute submacular hemorrhage (ASH): pneumatic displacement with C2F6, in combination with intravitreal injection of bevacizumab and rtPA, pars plana vitrectomy (PPV) with intravitreal injection of gas (C2F6), bevacizumab and subretinal injection of recombinant tissue plasminogen activator (rtPA), pars plana vitrectomy (PPV) with intravitreal injection of gas (C2F6), bevacizumab and intravitreal injection of recombinant tissue plasminogen activator (rtPA).<br />Methods: The study included 85 patients with ASH. In the group without PPV (A), patients were treated with intravitreal injection of C2F6, bevacizumab and rtPA. In the second and third group, patients underwent a PPV, intravitreal injection of bevacizumab, pneumatic displacement with C2F6 and a subretinal (B) or intravitreal (C) injection of recombinant tissue plasminogen activator (rt PA).<br />Results: In group A, mean BCVA increased from preop logMAR 1.41 to 1.05, in group B from 1.46 to 1.28 and in group C from 1.63 to 1.33. In group A, CFT changed from 764 ± 340 μm at time point 0 to 246 ± 153 μm at time point 1, in group B from 987 ± 441 μm to 294 ± 166 μm and in group C from 642 ± 322 μm to 418 ± 364 μm. Patients had an average of 5 injections after surgery.<br />Conclusion: Our study demonstrates that the three methods are equally effective in improving the morphology and the BCVA of patients with ASH.<br />Competing Interests: Competing interestsThe authors declare that they have no competing interests.<br /> (© The Author(s) 2020.)
Details
- Language :
- English
- ISSN :
- 2056-9920
- Volume :
- 6
- Database :
- MEDLINE
- Journal :
- International journal of retina and vitreous
- Publication Type :
- Academic Journal
- Accession number :
- 32637155
- Full Text :
- https://doi.org/10.1186/s40942-020-00228-x