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Adenohypophyseal hyperfunction syndromes and posterior pituitary tumors: prevalence, clinical characteristics, and pathophysiological mechanisms.
- Source :
-
Endocrine [Endocrine] 2020 Oct; Vol. 70 (1), pp. 15-23. Date of Electronic Publication: 2020 Jul 01. - Publication Year :
- 2020
-
Abstract
- Posterior pituitary tumors are rare nonneuroendocrine neoplasms originating in the neurohypophysis that lack hormonal secretory capacity. Surprisingly, these tumors are relatively frequently associated with adenohypophyseal syndromes of hormonal hypersecretion such as Cushing's disease and acromegaly. Fifteen cases of posterior pituitary tumor associated with hypercortisolism have been reported to date, 13 of them were pituicytomas (Pi) and 2 were granular cell tumors (GCT). Six patients with posterior pituitary tumor associated with acromegaly have been reported (4 Pi and 2 GCT). The main forms of clinical presentation and the possible pathophysiological mechanisms of this association are reviewed.
Details
- Language :
- English
- ISSN :
- 1559-0100
- Volume :
- 70
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Endocrine
- Publication Type :
- Academic Journal
- Accession number :
- 32613546
- Full Text :
- https://doi.org/10.1007/s12020-020-02399-x