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Characteristics of laboratory indexes in COVID-19 patients with non-severe symptoms in Hefei City, China: diagnostic value in organ injuries.
- Source :
-
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2020 Dec; Vol. 39 (12), pp. 2447-2455. Date of Electronic Publication: 2020 Jul 01. - Publication Year :
- 2020
-
Abstract
- This study compared the laboratory indexes in 40 non-severe COVID-19 patients with those in 57 healthy controls. In the peripheral blood system of non-severe symptom COVID-19 patients, lymphocytes, eosinophils, basophils, total procollagen type 1 amino-terminal propeptide, osteocalcin N-terminal, thyroid-stimulating hormone, growth hormone, and insulin-like growth factor-binding protein 3 significantly decreased, and total protein, albumin, alanine transaminase, alkaline phosphatase, γ-glutamyl transferase, activated partial thromboplastin time, prothrombin time, fibrinogen, D-dimer, fibrinogen degradation products, human epididymal protein 4, serum ferritin, and C-reactive protein were elevated. SARS-CoV-2 infection can affect hematopoiesis, hemostasis, coagulation, fibrinolysis, bone metabolism, thyroid, parathyroid glands, the liver, and the reproductive system.
- Subjects :
- Adult
Biomarkers blood
Bone and Bones metabolism
Bone and Bones pathology
Bone and Bones virology
C-Reactive Protein metabolism
COVID-19
Case-Control Studies
China epidemiology
Coronavirus Infections epidemiology
Coronavirus Infections pathology
Cross-Sectional Studies
Female
Ferritins blood
Fibrin Fibrinogen Degradation Products metabolism
Fibrinolysis
Hematopoiesis
Hemostasis
Humans
Liver metabolism
Liver pathology
Liver virology
Male
Middle Aged
Ovary metabolism
Ovary pathology
Ovary virology
Parathyroid Glands metabolism
Parathyroid Glands pathology
Parathyroid Glands virology
Pneumonia, Viral epidemiology
Pneumonia, Viral pathology
SARS-CoV-2
Serum Albumin metabolism
Severity of Illness Index
Testis metabolism
Testis pathology
Testis virology
Thyroid Gland metabolism
Thyroid Gland pathology
Thyroid Gland virology
Betacoronavirus pathogenicity
Coronavirus Infections blood
Coronavirus Infections diagnosis
Pandemics
Pneumonia, Viral blood
Pneumonia, Viral diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1435-4373
- Volume :
- 39
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 32613308
- Full Text :
- https://doi.org/10.1007/s10096-020-03967-9