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Is it Kawasaki shock syndrome, Kawasaki-like disease or pediatric inflammatory multisystem disease? The importance of semantic in the era of COVID-19 pandemic.
- Source :
-
RMD open [RMD Open] 2020 Jun; Vol. 6 (2). - Publication Year :
- 2020
-
Abstract
- A few weeks after the peak of the global 2019 novel coronavirus disease pandemic, cases of shock, multisystem inflammation and severe myocarditis have occurred in children and adolescents, generating some concerns and above all many questions. An almost immediate association raised with shock syndrome related to Kawasaki disease (KD). However, in light of bo/th experience and literature have taught us about severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection, and what already known on the epidemiology of KD, we suggest here the hypothesis of a new 'post-viral' systemic inflammatory disease related to excessive adaptive immune response rather than a form of KD caused by SARS-COV-2. We discuss analogies and differences between the two forms.<br />Competing Interests: Competing interests: IK-P has received consulting fees from AbbVie, Pfizer, Roche, CHUGAI, Novartis, SOBI and Novimmune. RC has no competing interests.<br /> (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Betacoronavirus isolation & purification
COVID-19
Child
Diagnosis, Differential
Disease Management
Humans
SARS-CoV-2
Terminology as Topic
Coronavirus Infections diagnosis
Coronavirus Infections epidemiology
Coronavirus Infections immunology
Coronavirus Infections physiopathology
Mucocutaneous Lymph Node Syndrome diagnosis
Mucocutaneous Lymph Node Syndrome epidemiology
Mucocutaneous Lymph Node Syndrome immunology
Pandemics
Pneumonia, Viral diagnosis
Pneumonia, Viral epidemiology
Pneumonia, Viral immunology
Pneumonia, Viral physiopathology
Systemic Vasculitis immunology
Systemic Vasculitis physiopathology
Systemic Vasculitis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2056-5933
- Volume :
- 6
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- RMD open
- Publication Type :
- Academic Journal
- Accession number :
- 32611651
- Full Text :
- https://doi.org/10.1136/rmdopen-2020-001333