Back to Search
Start Over
Vastus lateralis myocutaneous flap for ischial skin wound following the treatment of epithelioid sarcoma using pazopanib.
- Source :
-
Journal of wound care [J Wound Care] 2020 Jun 02; Vol. 29 (6), pp. 335-339. - Publication Year :
- 2020
-
Abstract
- Pazopanib, a targeted molecular drug, has been proposed as an effective treatment for soft tissue tumour and as a novel adjuvant therapy. There has been a paradoxical concern that wound healing could be inhibited by its anti-angiogenic properties, especially in reconstructive surgery. This paper reports on a 28-year-old woman who underwent flap surgery due to a skin and soft tissue injury after an effective treatment with pazopanib for refractory epithelioid sarcoma. The flap survived without any complication in off-periods of pazopanib for four weeks before and after the surgery, although it is only recommended that the washout periods of pazopanib commence at least seven days before scheduled surgery.
- Subjects :
- Adult
Angiogenesis Inhibitors administration & dosage
Buttocks
Combined Modality Therapy
Female
Humans
Indazoles
Magnetic Resonance Imaging
Pyrimidines administration & dosage
Sarcoma diagnostic imaging
Sulfonamides administration & dosage
Treatment Outcome
Wound Healing
Angiogenesis Inhibitors therapeutic use
Myocutaneous Flap
Pyrimidines therapeutic use
Quadriceps Muscle
Sarcoma therapy
Sulfonamides therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0969-0700
- Volume :
- 29
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of wound care
- Publication Type :
- Academic Journal
- Accession number :
- 32530777
- Full Text :
- https://doi.org/10.12968/jowc.2020.29.6.335