Abscopal effect of local irradiation treatment for thymoma: a case report.

Authors :: Guan S
Wang H
Qi XH
Guo Q
Zhang HY
Liu H
Zhu BJ
Source :: American journal of translational research [Am J Transl Res] 2020 May 15; Vol. 12 (5), pp. 2234-2240. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).
Publication Year :: 2020
Abstract: Introduction: With the rapid development of immunotherapy in recent years, growing clinical evidence suggests that a combination of radiotherapy and immunotherapy could improve the abscopal response rates and increase survival. However, observations on abscopal effects in patients receiving radiotherapy alone are still very rare. This study reports a rare case of a patient with type B3 thymoma with multiple lung metastases, who received localized irradiation.<br />Case Presentation: A 76-year-old Chinese woman was admitted to our hospital in November 2017, and her physical examination revealed a thymus mass with multiple lung metastases. Although the left lower lobe lesion was slightly larger than before, the patient presented with regression of the non-irradiated metastases after treatment with radiotherapy alone.<br />Conclusion: This patient experienced an apparent regression of metastatic mass, suggesting a radiation-induced abscopal effect.<br />Competing Interests: None.<br /> (AJTR Copyright © 2020.)

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