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Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells.
- Source :
-
The Analyst [Analyst] 2020 Jun 15; Vol. 145 (12), pp. 4260-4264. - Publication Year :
- 2020
-
Abstract
- Copper (Cu) is a vital metal element for humans and animals. Monitoring and evaluating the concentration level of Cu2+ in a biological body is an effective way to prevent a variety of diseases. In this work, phenyl doped graphitic carbon nitride (PDCN) nanosheets with strong green fluorescence exhibited a sensitive and selective detection for Cu2+ with a linear range from 0.1-2.0 μmol L-1. Furthermore, fluorescent imaging was applied to semiquantitatively detect Cu2+ in HeLa cells using PDCN nanosheets as the probe, which can avoid the interference of background autofluorescence. This work provided a low-cost and biologically friendly fluorescent probe to monitor the concentration level of Cu2+ in living cells.
Details
- Language :
- English
- ISSN :
- 1364-5528
- Volume :
- 145
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 32494796
- Full Text :
- https://doi.org/10.1039/d0an00795a