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Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health.

Authors :
Salehi B
Machin L
Monzote L
Sharifi-Rad J
Ezzat SM
Salem MA
Merghany RM
El Mahdy NM
Kılıç CS
Sytar O
Sharifi-Rad M
Sharopov F
Martins N
Martorell M
Cho WC
Source :
ACS omega [ACS Omega] 2020 May 14; Vol. 5 (20), pp. 11849-11872. Date of Electronic Publication: 2020 May 14 (Print Publication: 2020).
Publication Year :
2020

Abstract

Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.<br />Competing Interests: The authors declare no competing financial interest.<br /> (Copyright © 2020 American Chemical Society.)

Details

Language :
English
ISSN :
2470-1343
Volume :
5
Issue :
20
Database :
MEDLINE
Journal :
ACS omega
Publication Type :
Academic Journal
Accession number :
32478277
Full Text :
https://doi.org/10.1021/acsomega.0c01818