DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents.

Authors :: Casellas Román HL
Venugopal K
Feng Y
Shabashvili DE
Posada LM
Li J
Guryanova OA
Source :: Leukemia research [Leuk Res] 2020 Jul; Vol. 94, pp. 106372. Date of Electronic Publication: 2020 May 13.
Publication Year :: 2020

Subjects :: Animals
DNA Methyltransferase 3A
Mice
Mice, Transgenic
DNA (Cytosine-5-)-Methyltransferases genetics
DNA (Cytosine-5-)-Methyltransferases metabolism
Decitabine pharmacology
Leukemia, Myeloid, Acute enzymology
Leukemia, Myeloid, Acute genetics
Leukemia, Myeloid, Acute pathology
Myelodysplastic Syndromes drug therapy
Myelodysplastic Syndromes enzymology
Myelodysplastic Syndromes genetics
Myelodysplastic Syndromes pathology
Neoplasm Proteins genetics
Neoplasm Proteins metabolism

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