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Palladium-Catalyzed Amination/Dearomatization Reaction of Indoles and Benzofurans.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2020 Jun 19; Vol. 85 (12), pp. 7817-7839. Date of Electronic Publication: 2020 Jun 01. - Publication Year :
- 2020
-
Abstract
- This report describes a palladium-catalyzed dearomatization and amination tandem reaction of 2,3-disubstituted indoles and benzofurans via the Catellani strategy. This reaction provides a new method for the construction of amino-substituted indoline-fused cyclic and benzofuran spiro compounds in good yields. The reaction has broad functional group compatibility and substrate scope.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 85
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 32441518
- Full Text :
- https://doi.org/10.1021/acs.joc.0c00475