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Oxygen Sensing Comes to the Development of the Cerebellum.
- Source :
-
Neuron [Neuron] 2020 May 20; Vol. 106 (4), pp. 554-555. - Publication Year :
- 2020
-
Abstract
- In this issue of Neuron, Kullmann et al. (2020) demonstrate that the hypoxic state of the developing cerebellum stimulates Hif1a expression to maintain cell proliferation until vascularization creates normoxic conditions, activating Pard polarity signaling complex genes and stimulating cells to cease proliferation and begin migration.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Subjects :
- Cell Proliferation
Cerebellum
Neurons
Oxygen
Signal Transduction
Subjects
Details
- Language :
- English
- ISSN :
- 1097-4199
- Volume :
- 106
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Neuron
- Publication Type :
- Academic Journal
- Accession number :
- 32437652
- Full Text :
- https://doi.org/10.1016/j.neuron.2020.05.002