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Early Outcomes of Outpatient Management of Kidney Transplant Recipients with Coronavirus Disease 2019.

Authors :
Husain SA
Dube G
Morris H
Fernandez H
Chang JH
Paget K
Sritharan S
Patel S
Pawliczak O
Boehler M
Tsapepas D
Crew RJ
Cohen DJ
Mohan S
Source :
Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2020 Aug 07; Vol. 15 (8), pp. 1174-1178. Date of Electronic Publication: 2020 May 18.
Publication Year :
2020

Abstract

Background and Objectives: Outcomes of kidney transplant recipients diagnosed with coronavirus disease 2019 as outpatients have not been described.<br />Design, Setting, Participants, & Measurements: We obtained clinical data for 41 consecutive outpatient kidney transplant recipients with known or suspected coronavirus disease 2019. Chi-squared and Wilcoxon rank sum tests were used to compare characteristics of patients who required hospitalization versus those who did not.<br />Results: Of 41 patients, 22 (54%) had confirmed coronavirus disease 2019, and 19 (46%) were suspected cases. Patients most commonly reported fever (80%), cough (56%), and dyspnea (39%). At the end of follow-up, 13 patients (32%) required hospitalization a median of 8 days (range, 1-16) after symptom onset, and 23 (56%) had outpatient symptom resolution a median of 12 days (4-23) after onset. Patients who required hospitalization were more likely to have reported dyspnea (77% versus 21%, P =0.003) and had higher baseline creatinine (median, 2.0 versus 1.3 mg/dl, P =0.02), but there were no other differences between groups.<br />Conclusions: In an early cohort of outpatient kidney transplant recipients with known or suspected coronavirus disease 2019, many had symptomatic resolution without requiring hospitalization.<br /> (Copyright © 2020 by the American Society of Nephrology.)

Details

Language :
English
ISSN :
1555-905X
Volume :
15
Issue :
8
Database :
MEDLINE
Journal :
Clinical journal of the American Society of Nephrology : CJASN
Publication Type :
Academic Journal
Accession number :
32423908
Full Text :
https://doi.org/10.2215/CJN.05170420