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Immunoglobulins in the treatment of COVID-19 infection: Proceed with caution!
- Source :
-
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2020 Jul; Vol. 216, pp. 108459. Date of Electronic Publication: 2020 May 11. - Publication Year :
- 2020
-
Abstract
- The COVID-19 pandemic is one of the greatest infectious challenges in recent history. Presently, few treatment options exist and the availability of effective vaccines is at least one year away. There is an urgent need to find currently available, effective therapies in the treatment of patients with COVID-19 infection. In this review, we compare and contrast the use of intravenous immunoglobulin and hyperimmune globulin in the treatment of COVID-19 infection.<br />Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest.<br /> (Published by Elsevier Inc.)
- Subjects :
- Adaptive Immunity drug effects
Angiotensin-Converting Enzyme 2
Antibody-Dependent Enhancement drug effects
Betacoronavirus immunology
Betacoronavirus pathogenicity
COVID-19
Coronavirus Infections epidemiology
Coronavirus Infections immunology
Coronavirus Infections therapy
Coronavirus Infections virology
Cytokine Release Syndrome etiology
Cytokine Release Syndrome immunology
Cytokine Release Syndrome prevention & control
Gene Expression
Humans
Immunity, Innate drug effects
Immunization, Passive adverse effects
Immunization, Passive methods
Immunoglobulins, Intravenous adverse effects
Immunologic Factors adverse effects
Molecular Targeted Therapy
Peptidyl-Dipeptidase A genetics
Peptidyl-Dipeptidase A immunology
Pneumonia, Viral epidemiology
Pneumonia, Viral immunology
Pneumonia, Viral virology
SARS-CoV-2
Spike Glycoprotein, Coronavirus genetics
Spike Glycoprotein, Coronavirus immunology
T-Lymphocytes drug effects
T-Lymphocytes immunology
T-Lymphocytes virology
COVID-19 Serotherapy
Betacoronavirus drug effects
Coronavirus Infections drug therapy
Cytokine Release Syndrome pathology
Immunoglobulins, Intravenous administration & dosage
Immunologic Factors administration & dosage
Pandemics
Pneumonia, Viral drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1521-7035
- Volume :
- 216
- Database :
- MEDLINE
- Journal :
- Clinical immunology (Orlando, Fla.)
- Publication Type :
- Academic Journal
- Accession number :
- 32418917
- Full Text :
- https://doi.org/10.1016/j.clim.2020.108459